Products

PEARLITOL
Mannitol USP/NF, EP, JP and Mannitol IP

Mannitol is a polyol manufactured by catalytic hydrogenation of starch, a natural raw material of vegetable origin. It occurs as a slightly sweet, white crystalline powder that gives a cooling sensation on dissolution in the mouth.

It has excellent stability, low hygroscopicity and good solubility in different solvents. It forms an ideal excipient for solid orals as well as injectable dosage forms and can be used for wet or dry granulation and direct compression. It also serves as a cryoprotective agent in freeze drying applications. Mannitol has low calorific values, is non-cariogenic and ideal for sugar-free formulations.

Besides Pearlitol grades manufactured in France and USA, Roquette also provides Mannitol IP from their China facility.

Crystalline Mannitol
 

Grade

Mean Diameter
(μm)

Type

Applications

 

Pearlitol 25 C

25

Extra-fine

Diluent for tablets, capsules and sachets, excipient for chemically unstable or moisture sensitive actives and orodispersible forms, freeze-drying carrier and sweetener for pharmaceutical chewing gums

Pearlitol 50 C

50

Fine

Pearlitol 160 C

160 Standard

Ramritol 60 IP

~160

Standard

Pearlitol PF

-

Pyrogen-free

Diuretic-osmotic agent for injectable solutions and also used as a cryoprotectant for freeze dried injectables



Granular Mannitol
 

 

Grade

Mean Diameter

(μm)

Type

Applications

Pearlitol 100 SD                 

100

Spray-dried      

Diluent for direct compression especially for chewable, effervescent and orodispersible tablets, ideal excipient for chemically unstable or moisture sensitive actives and also diluent for capsules and sachets

PEARLITOL 150 SD                    

150

Pearlitol 200 SD

180

Pearlitol 200 GT

160

Granulated

Designed to solve formulation challenges by limiting capping, improving tableting speed and easing production of smaller sized tablets

Pearlitol 300 DC

250

Granulated grades are high density mannitol. It functions as an excellent diluent for direct compression based fast dissolving tablets and chewable tablets

Pearlitol 400 DC

360

 

This browser is not supported. For a better experience on Signet, update your browser.