Products

METOLOSE
Hypromellose USP/NF, EP, JP and Methylcellulose USP/NF, EP, JP

Metolose is a non-ionic, water soluble cellulose ether derived from highly purified natural pulp by initial treatment with caustic soda to obtain alkali-cellulose, followed by etherification with methyl chloride or with the combination of methyl chloride and propylene oxide.

It can be used as a binder for solid dosage forms and enjoys a variety of properties such as water retention, thickening, sustained-release and protective colloid.

Metolose consists of methylcellulose and three substitution types of hypromellose each available in several grades of differing viscosity. Shin-Etsu also manufactures Metolose SR grades specifically for use in hydrophilic sustained-release matrix systems.

Hypromellose
 

Grade

Description

Applications

Viscosity
(cps)

USP

Substitution Type

Metolose 60SH-50

50

2910

Used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules

 

Also used for ophthalmic formulations

Metolose 60SH-4000

4000

Metolose 60SH-10000

10000

Metolose 65SH-50

50

2906

Metolose 65SH-4000

4000

Metolose 90SH-4000

4000

2208

Metolose 90SH-15000

15000

Metolose 90SH-100000

100000

Metolose 90SH-100SR

100

2208

Special HPMC grades, used as hydrophilic matrix agents allowing more controllable and reproducible drug release, along with good consistency in the final product

Metolose 90SH-4000SR

4000

Metolose 90SH-15000SR

15000

Metolose 90SH-100000SR

100000



Methylcellulose
 

Grade

Description

Applications

Viscosity

(cps)

USP

Substitution Type

Metolose SM-4

4

-

Polymer for granule coating

Metolose SM-15

15

-

Used as a granulating agent, emulsifying agent, thickener and bulk laxative

Metolose SM-400

400

-

Metolose SM-4000

4000

-

This browser is not supported. For a better experience on Signet, update your browser.