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  • SYNTHETIC PHOSPHOLIPIDS and OTHER SYNTHETIC LIPIDS

SYNTHETIC PHOSPHOLIPIDS and OTHER SYNTHETIC LIPIDS

Phospholipids are amphiphilic naturally occurring molecules which are the primary constituents of cell membranes. These represent excellent building blocks for drug delivery systems due to their high degree of biocompatibility and the enormous diversity of possible structures. The functional properties of various phospholipids are determined by the nature of their polar headgroups and fatty acid composition.

Corden Pharma synthesizes highly purified phospholipids starting from (S)-1,2-isopropylideneglycerol with well controlled and consistent batch-to-batch quality rendering them suitable as pharmaceutical excipients.

Product

Grade

Applications

Monoglycerols

Monocaprin, Monolaurin, Monomyristin

Drug delivery technologies such as liposomes, emulsions and pulmonary particles.  Also, used as an API in drug products

Diacylglycerols

DLG, DMG, DPG, DPyG, DSG

Phosphatidic Acids

DLPA Na, DMPA Na, DPPA Na, DSPA Na

Phosphoglycerols

DLPG Na, DMPG Na, DMP-sn -1-G NH4, DPPG Na, DSPG Na, DSP-sn -1-G Na

Phosphoserines

DPPS Na

Phosphoethanolamines

DLPE, DMPE, DOPE, DPPE, 1,3-DPPE, DPyPE, DSPE

Phosphocholines

DAPC, DLPC, DMPC, DOPC, DPPC, DPePC Chloride, DPePC Triflate, DSPC

MPEGylated Phospholipids

MPEG-2000-DMPE, MPEG-5000-DMPE, MPEG-2000-DPPE, MPEG-5000-DPPE, MPEG-750-DSPE, MPEG-2000-DSPE, MPEG-5000-DSPE

Phospholipids with Heterogeneous Fatty Acid Chains

PLPC, POPC, SMPC, 1,3-POPE

 

Phosphoglycerols with Heterogeneous Fatty Acid Chains

POPG Na, POPG NH4

 

Sodium Cholesteryl Sulfate

Sodium Cholesteryl Sulfate

2-Lyso-phospholipids

P-lyso-PC, P-lyso-PC (short route),
S-lyso-PC, S-lyso-PC (short route)

Ether Lipids

1-O-Octadecyl-2-O-methyl-sn-glycerol

Cationics

DODMA, DOTAP Cl

Fatty Acids

Oleic acid, Palmitic acid, Stearic acid, Myristic acid

 

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